Chemical Measurement Capabilities
Our chemical measurement capabilities can be applied to environmental monitoring, food testing, toxicity assessments, as well as disease diagnostics, monitoring and therapeutics.
We can detect, accurately quantify and identify elements, particles, small organic molecules and proteins in consumer products, food, environmental and clinical samples.
Our chemical measurement research focuses on developing reference methods and materials for high accuracy elemental, isotope ratio and speciation analysis; purity determination, bio-imaging; particle characterisation and quantification; small molecule, peptide and protein quantification and structural characterisation.
Sample preparation and separation capabilities
- Advanced sample preparation
Laser ablation and enhanced extraction - Extraction
ASE, SPE and QuEChERS - Separation
uPLC, CapLC, GC, LCxLC, GCxGC and nanoLC - Field Flow Fractionation
Organic mass spectrometry capabilities
- 17 Mass spectrometers
- QQQ, QTOF, qMS, IMS, ITMS, MALDITOFTOF, TOF and Orbitrap
- HDX-MS
- Direct and ambient MS
- Collaboration with Agilent, Bruker, Sciex, Thermo and Waters
Inorganic analysis capabilities
- 8 ICPs and 1IRMS
- 7 ICP-MS: ICP-TOF, QQQ, Q, and Multi-collector ICP-MS
- 1 ICP-OES
- Multi-Collector ICP-MS
- Light scattering detection (MALS, MADLS, PTA)
- LD-IR
- Optical Particle Imaging
- Collaboration with Agilent, Thermo, ToFWerk, Postnova Analytics, Malvern Panalytical
Purity assignment capabilities
Using a mass balance approach or direct assay for the purity of organic material, including:
- Water determination by oven Karl Fischer (ISO 17025*)
- HPLC-UV (ISO 17025*)
- GC-FID (ISO 17025*)
- DSC (ISO 17025*)
- TGA-MS for water, volatiles and inorganic content
- Quantitative NMR (qNMR, ISO 17025 *)
- Alcohol content by titration (ISO 17025*)
*ISO accreditation is held by host organisation LGC
Nuclear magnetic resonance (NMR) spectroscopy capabilities
- Bruker 600 MHz solution state
- Qualitative and quantitative measurements (rapid)
- Small sample mass (mgs) requirements with minimum sample preparation and non-destructive
- Bench top/low field NMR with flow probe and alternative nuclei detection to 1H
Resources
Our work makes a difference, helping to solve some of the biggest challenges of our time. Discover how we apply our chemical measurement capabilities through our case studies, publications and updates.
Get in touch
If you’re interested in exploring partnership opportunities with the NML or learning more about our measurement capabilities, we’d love to hear from you.